Alkaline phosphatase is an enzyme that releases inorganic phosphate from phosphoric esters, necessary for mineralization. There are several isoenzymes and, among them bone, has been considered a good marker of osteoblastic activity.
many compounds have been demonstrated to exhibits osteogenic activity in vitro. However, if you are asking for standard compounds or drugs for comparing and validating osteogenesis inducing property by your compound of interest, then I will suggest you to use either estrogen or PTHrP f(1-34) fragment.
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